Cleanance Comedomed hydrates, mattifies, helps reduce blemishes and limit their reappearance. Within this cutting-edge formula is 25% Comedoclastin™, an innovative plant-based active ingredient derived from Milk Thistle, to help reduce excess sebum and prevent blemishes. Moreover, Comedomed is enriched with 67.5% Avène Thermal Spring Water to soothe, soften and comfort sensitive skin. With only nine ingredients, Comedomed has proven efficacy from seven days*. 90% of subjects said their skin was clearer in just 7 days*. Suitable for acne-prone skin, the light texture and quick absorption gives a non-sticky and non-greasy effect, leaving the skin feeling silky smooth. It can be used alone or in combination with medicinal acne treatments (should not be used with oral Isotretinoin). Suitable for adults and adolescents.